Use Modafinil (Provigil) specifically as directed about the label, or as prescribed by your health practitioner. Don't use in much larger or lesser quantities or for more time than encouraged.

cyclophosphamide will boost the degree or impact of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.

Hold a listing of all of your medicines with you, and share this information using your medical doctor and pharmacist. Test along with your overall health care Expert or health practitioner For extra clinical guidance, or if you have overall health thoughts, fears or To find out more concerning this medicine.

As a consequence of inconsistencies amongst the drug labels on DailyMed and the capsule images supplied by RxImage, we now not Show the RxImage tablet images connected to drug labels.

rifampin will reduce the extent or outcome of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Not known.

Edgar and Seidel (1997) investigated the effects of modafinil on rest-wake EEG and locomotor activity in Stay rats compared with the results of methamphetamine. They found that modafinil improved locomotor activity only marginally unlike methamphetamine which induced profound will increase in locomotor exercise.

Modafinil is usually a wakefulness-promoting agent with confirmed nootropic Attributes. Its success has been very well-documented in dozens of studies more check here than a long time of analysis, and it's typically made use of off-label by healthy individuals who want to enhance their psychological effectiveness.

Sebban et al published 2 reports in 1999 applying eletroen-cephalography in live rats to test modafinil along with the general dopamine receptor antagonist clozapine or even the selective D2 antagonist raclopride. They discovered that modafinil bolstered the EEG synchronization attributable to raclopride, and it had been able to attenuate in equally cortices the synchronizing outcomes of clozapine, that has an α1 adrenergic receptor antagonist Qualities.

Beginning Management tablets together with other hormone-dependent birth Handle may well not perform as well to avoid pregnancy. Use Several other kind of start Regulate also, like a condom, when taking modafinil and for 1 thirty day period once the past dose.

etravirine will reduce the level or result of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

Clopidogrel efficacy might be lowered by medicines that inhibit CYP2C19. Inhibition of platelet aggregation by clopidogrel is entirely resulting from an Energetic metabolite. Clopidogrel is metabolized to this Lively metabolite partly by CYP2C19. .

Engber et al (1998) calculated glucose utilization with 2-deoxyglucose autoradiography inside the brains of rats supplied modafinil, plus they discovered that modafinil amplified glucose utilization inside the thalamus, hippocampus, subiculum, as well as the amygdala, Nonetheless they pointed out that Substantially with the glucose utilization while in the brain might be during the mitochondria of axons and dendrites rather then mobile somas.

Discontinue interfering medication for a minimum of 5 half-life just before administration of either the dosimetry or an iobenguane dose. Never administer these medicines till not less than 7 days immediately after Every iobenguane dose.

Hazard of pores and skin reactions, discontinue if rash or other hypersensitivity reactions arise. Could impair ability to function large equipment and complete hazardous jobs